Reaction: Flipping of dolichyl-phosphate-glucose into the ER lumen
- in pathway: Synthesis of dolichyl-phosphate-glucose
Dolichyl-phosphate-glucose is flipped toward the luminal side of the ER membrane (Imbach T et al, 1999). The exact mechanism and proteins involved in this step are not clear yet, but it is known that it must be carried out by a different flippase than the one that catalyzes the flipping of the N-glycan precursor (Sanyal S et al, 2008).
Reaction - small molecule participants:
DbGP [integral component of lumenal side of endoplasmic reticulum membrane]
DbGP [integral component of cytoplasmic side of endoplasmic reticulum membrane]
Reactome.org reaction link: R-HSA-446211
======
Reaction input - small molecules:
dolichyl beta-D-glucosyl phosphate
Reaction output - small molecules:
dolichyl beta-D-glucosyl phosphate
Reactome.org link: R-HSA-446211