Reaction: Synthesis of dolichyl-phosphate-glucose
- in pathway: Synthesis of dolichyl-phosphate-glucose
Dolichyl-phosphate beta-glucosyltransferase (ALG5) associated with the endoplasmic reticulum (ER) membrane catalyzes the reaction of cytosolic UDP-glucose with dolichyl phosphate exposed on the cytosolic face of the ER membrane to form Dolichyl-P-glucose with its glucose moiety oriented toward the cytosol (Imbach T et al, 1999).
Reaction - small molecule participants:
DbGP [integral component of cytoplasmic side of endoplasmic reticulum membrane]
UDP [cytosol]
DOLP [integral component of cytoplasmic side of endoplasmic reticulum membrane]
UDP-D-glucose(2-) [cytosol]
Reactome.org reaction link: R-HSA-446214
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Reaction input - small molecules:
dolichyl phosphate(2-)
UDP-D-glucose(2-)
Reaction output - small molecules:
dolichyl beta-D-glucosyl phosphate
UDP(3-)
Reactome.org link: R-HSA-446214