Reaction: Aquaporins passively transport water into cells
- in pathway: Passive transport by Aquaporins
Aquaporin-0 (AQP0, also known as MIP), AQP1, AQP2, AQP3, AQP4, AQP5, AQP6, AQP7, AQP8, AQP9, AQP10 and AQP11 are 6-pass transmembrane proteins that passively transport water across the plasma membrane according to the concentration gradient. Each molecule contains a water channel and subunits assemble into homotetramers. In principle water can move in either direction through an aquaporin, however in vivo flow may occur in only one direction. Conductance of water by AQP0 and AQP11 are low relative to other aquaporins. AQP11 and AQP12 are not fully characterised and their ability to to allow transport of water is still debated .
Reaction - small molecule participants:
H2O [extracellular region]
H2O [cytosol]
Reactome.org reaction link: R-HSA-507868
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Reaction input - small molecules:
water
Reaction output - small molecules:
water
Reactome.org link: R-HSA-507868