Reaction: FYN phosphorylates PAK2
- in pathway: VEGFA-VEGFR2 Pathway
PAK2 activity via GTPases can be strongly potentiated by concurrent stimulation of cellular tyrosine kinase activity. FYN may be involved in this potentiation by phosphorylating Y130 in the N-terminal regulatory domain leading to a robust enhancement of the catalytic activity of PAK2 (Renkema et al. 2002).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-5218812
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-5218812