Reaction: GLTP transports GSL from plasma membrane to ER membrane
- in pathway: Glycosphingolipid biosynthesis
Glycolipid transfer protein (GLTP) is a monomeric, soluble protein that can mediate the intermembrane transport of glycosphingolipids (GSLs) (Malinina et al. 2004, Malinina et al. 2006, Tuuf & Mattjus 2007). GLTPs could serve as potential regulators of cell processes mediated by GSLs such as differentiation and proliferation to invasive adhesion, neurodegeneration and apoptosis. This reaction shows one example of GSL transfer from the plasma membrane to ER membrane.
Reaction - small molecule participants:
GSL [endoplasmic reticulum membrane]
GSL [plasma membrane]
Reactome.org reaction link: R-HSA-5340320
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Reaction input - small molecules:
glycosphingolipid
Reaction output - small molecules:
glycosphingolipid
Reactome.org link: R-HSA-5340320