Reaction: Translocation of peptidyl-tRNA from A-site to P-site (and translocation of 55S ribosome by 3 bases along mRNA)
- in pathway: Mitochondrial translation elongation
GFM1 (EF-Gmt, EF-G1mt) of the GFM1:GTP complex hydrolyzes GTP, yielding GFM1:GDP (Tsuboi et al. 2009). The hydrolysis of GTP drives translocation of the peptidyl-tRNA from the A-site to the P-site with consequent ejection of the deacylated tRNA from the P-site and translocation of the ribosome in the 3' direction along the mRNA (Bhargava et al. 2004, Tsuboi et al. 2009, inferred from bovine homologs in Chung and Spremulli 1990).
Reaction - small molecule participants:
Pi [mitochondrial matrix]
Reactome.org reaction link: R-HSA-5419279
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Reaction input - small molecules:
Reaction output - small molecules:
hydrogenphosphate
Reactome.org link: R-HSA-5419279