Reaction: AFBDHD hydrolyses non-enzymatically to AFBDHO
- in pathway: Aflatoxin activation and detoxification
Aflatoxin B1-8,9-dihydrodiol (AFBDHD) undergoes base-catalysed rearrangement to aflatoxin B1 dialdehyde (AFBDHO) that can react with protein lysine residues (not shown here) (Guengerich et al. 1998).
Reaction - small molecule participants:
AFBDHO [cytosol]
H2O [cytosol]
AFBDHD [cytosol]
Reactome.org reaction link: R-HSA-5423694
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Reaction input - small molecules:
water
aflatoxin B1 8,9-dihydrodiol
Reaction output - small molecules:
aflatoxin B1 dialdehyde
Reactome.org link: R-HSA-5423694