Reaction: ACY1:Zn2+ dimer hydrolyses mercapturic acids
- in pathway: Aflatoxin activation and detoxification
Cytosolic aminocyclases 1 and 3 (ACY1,3) can hydrolyse N-acylated amino acids and N-acylcysteine-S-conjugates (Lindner et al. 2003). They are functional as dimers and utilise zinc as a cofactor.
Reaction - small molecule participants:
CH3COO- [Golgi lumen]
H2O [cytosol]
Reactome.org reaction link: R-HSA-5433074
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Reaction input - small molecules:
water
Reaction output - small molecules:
acetic acid
Reactome.org link: R-HSA-5433074