Reaction: Phosphorylation of SHC1 by p-5Y-EGFRvIII
- in pathway: Constitutive Signaling by EGFRvIII
EGFRvIII cancer mutant was not directly tested for its ability to phosphorylate SHC1, but is assumed to interact with SHC1 in the same way as the wild-type EGFR protein (Soler et al. 1994, VanderKuur et al. 1995).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-5637796
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-5637796