Reaction: NEIL1 cleaves DHU from damaged DNA
- in pathway: Cleavage of the damaged pyrimidine
NEIL1 acts as a DNA glycosylase to remove dihydrouracil (DHU) from damaged DNA (Hazra et al. 2002).
Reaction - small molecule participants:
DHU [nucleoplasm]
Reactome.org reaction link: R-HSA-5649658
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Reaction input - small molecules:
Reaction output - small molecules:
5,6-dihydrouracil
Reactome.org link: R-HSA-5649658