Reaction: USP43 deISGylates ISG:K164,ISG:K168-PCNA
- in pathway: Termination of translesion DNA synthesis
USP43 acts as an ISG15 protease to cleave ISG15 from lysines K164 and K168 of PCNA, thus deISGylating PCNA (Park et al. 2014).
Reaction - small molecule participants:
H2O [nucleoplasm]
Reactome.org reaction link: R-HSA-5653786
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Reaction input - small molecules:
water
Reaction output - small molecules:
Reactome.org link: R-HSA-5653786