Reaction: SLC2A1 tetramer transports Glc from cytosol to Golgi lumen
- in pathway: Lactose synthesis
SLC2A1 (aka GLUT1) tetramer in the Golgi membrane mediates the facilitated diffusion of glucose from the cytosol into the Golgi lumen. SLC2A1, normally confined to the plasma membrane, is also abundant in the Golgi membranes of epithelial cells of the lactating mammary gland, as demonstrated experimentally in mice (Nemeth et al. 2000). It is not known how this physiological state-specific relocalization is regulated.
Reaction - small molecule participants:
Glc [Golgi lumen]
Glc [cytosol]
Reactome.org reaction link: R-HSA-5653873
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Reaction input - small molecules:
alpha-D-glucose
Reaction output - small molecules:
alpha-D-glucose
Reactome.org link: R-HSA-5653873