Reaction: MT1A binds arsenic
- in pathway: Metallothioneins bind metals
Metallothionein MT1A binds 6 atoms of arsenic(III), 3 atoms at the N-terminal beta domain and 3 atoms at the C-terminal alpha domain (Ngu and Stillman 2006, Irvine et al. 2013). Each arsenic atom binds 3 cysteine thiols (Ngu and Stillman 2006, Irvine et al. 2013).
Reaction - small molecule participants:
As3+ [cytosol]
Reactome.org reaction link: R-HSA-5661230
======
Reaction input - small molecules:
arsenic(3+)
Reaction output - small molecules:
Reactome.org link: R-HSA-5661230