Reaction: CRYL1 dimer dehydrogenates L-gulonate to 3-dehydro-L-gulonate
- in pathway: Formation of xylulose-5-phosphate
Cytosolic CRYL1 (lambda-crystallin homolog, also known as L-gulonate 3-dehydrogenase) dimer catalyzes the NAD-dependent dehydrogenation of L-gulonate to form 3-dehydro-L-gulonate. The CRYL1 protein also functions as a lens crystallin, hence its name (Ishikura et al. 2005).
Reaction - small molecule participants:
H+ [cytosol]
3-dehydro-L-gulonate [cytosol]
NADH [cytosol]
L-gulonate [cytosol]
NAD+ [cytosol]
Reactome.org reaction link: R-HSA-5661290
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Reaction input - small molecules:
L-gulonate
NAD(1-)
Reaction output - small molecules:
hydron
3-dehydro-L-gulonate
NADH(2-)
Reactome.org link: R-HSA-5661290