Reaction: MT2A binds copper
- in pathway: Metallothioneins bind metals
The metallothionein MT2A binds 10 atoms of copper(I). Complexes with up to 12 atoms of Cu+ are observed, however the predominant form appears to be MT2A:10Cu+ (Banci et al. 2010, Chung et al. 2010). Metallothioneins and CuZn-SOD have the highest affinities of cellular proteins for copper(I), but metallothioneins are incapable of removing copper from other cellular enzymes (Banci et al. 2010).
Reaction - small molecule participants:
Cu1+ [cytosol]
Reactome.org reaction link: R-HSA-5662986
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Reaction input - small molecules:
copper(1+)
Reaction output - small molecules:
Reactome.org link: R-HSA-5662986