Reaction: PAK1 phosphorylates FLNA
- in pathway: RHO GTPases activate PAKs
Activated PAK1 phosphorylates FLNA (filamin A) on serine residue S2152 in vitro and in vivo. FLNA is involved in PAK1-induced formation of membrane ruffles (Vadlamudi et al. 2002).
Reaction - small molecule participants:
ADP [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-5669250
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-5669250