Reaction: Leucodopachrome, L-Dopaquinone transform to Dopachrome, L-Dopa
- in pathway: Melanin biosynthesis
A redox exchange between leucodopachrome (cyclodopa) and dopaquinone gives rise to dopachrome, an orange-red intermediate (Raper 1927, Mason et al. 1948) and dopa. This reaction is considered the source of dopa formed during melanogenesis (Ito & Wakamatsu 2008).
Reaction - small molecule participants:
Dopachrome [melanosome lumen]
L-Dopa [melanosome lumen]
L-Dopaquinone [melanosome lumen]
Leucodopachrome [melanosome lumen]
Reactome.org reaction link: R-HSA-5672019
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Reaction input - small molecules:
L-dopaquinone
leucodopachrome
Reaction output - small molecules:
dopachrome
L-dopa zwitterion
Reactome.org link: R-HSA-5672019