Reaction: KCNJ11:ABCC9 transports K+ from extracellular region to cytosol
- in pathway: ABC-family proteins mediated transport
ATP-sensitive inward rectifier potassium channel 11 (KCNJ11) is an inward rectifier potassium channel, favouring potassium flow into the cell rather than out of it. KCNJ11 can complex with ATP-binding cassette sub-family member 9 (ABCC9) to form cardiac and smooth muscle-type K+(ATP) channels. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (Babenko et al. 1998, Tammaro & Ashcroft 2007).
Reaction - small molecule participants:
K+ [cytosol]
K+ [extracellular region]
K+ [cytosol]
K+ [extracellular region]
Reactome.org reaction link: R-HSA-5678261
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Reaction input - small molecules:
potassium(1+)
potassium(1+)
Reaction output - small molecules:
potassium(1+)
potassium(1+)
Reactome.org link: R-HSA-5678261