Reaction: MIOX oxidises Ins to GlcA
- in pathway: Synthesis of IP2, IP, and Ins in the cytosol
Inositol oxidase (MIOX) catalyses the oxidation of inositol (Ins) to glucuronic acid (GlcA). MIOX binds two Fe2+ ions as cofactor (Arner et al. 2004, Thorsell et al. 2008).
Reaction - small molecule participants:
H2O [cytosol]
H+ [cytosol]
GlcA [cytosol]
O2 [cytosol]
Ins [cytosol]
Reactome.org reaction link: R-HSA-5678327
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Reaction input - small molecules:
dioxygen
myo-inositol
Reaction output - small molecules:
water
hydron
D-glucuronate
Reactome.org link: R-HSA-5678327