Reaction: PPP5C dephosphorylates TP53BP1
- in pathway: Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
PPP5C-mediated dephosphorylation of TP53BP1 serine residues S25 and S1778 contributes to dissociation of TP53BP1 from DNA doubles strand break (DSB) sites and termination of DSB repair (Kang et al. 2009).
Reaction - small molecule participants:
Pi [nucleoplasm]
H2O [nucleoplasm]
Reactome.org reaction link: R-HSA-5683405
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Reaction input - small molecules:
water
Reaction output - small molecules:
hydrogenphosphate
Reactome.org link: R-HSA-5683405