Reaction: CHEK1 phosphorylates BRCA2
CHEK1 phosphorylates BRCA2 on threonine residue T3887, in the C-terminal region of BRCA2. CHEK1-mediated BRCA2 phosphorylation, as well as CHEK1 mediated RAD51 phosphorylation, promotes the association of BRCA2 with RAD51 (Bahassi et al. 2008).
Reaction - small molecule participants:
ADP [nucleoplasm]
ATP [nucleoplasm]
Reactome.org reaction link: R-HSA-5685242
======
Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-5685242