Reaction: SIRT5 deacetylates Cytochrome C
- in pathway: Transcriptional activation of mitochondrial biogenesis
Sirtuin 5 has been shown to deacetylate Cytochrome C in the the mitochondrial intermembrane space (Schlicker et al. 2008). The functional significance of this is unknown (Bao & Sack 2010).
Reaction - small molecule participants:
NAM [mitochondrial intermembrane space]
2'-O-acetyl-ADP-ribose [mitochondrial intermembrane space]
NAD+ [mitochondrial intermembrane space]
Reactome.org reaction link: R-HSA-5688294
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Reaction input - small molecules:
NAD(1-)
Reaction output - small molecules:
nicotinamide
2''-O-acetyl-ADP-D-ribose
Reactome.org link: R-HSA-5688294