Reaction: USP10,USP24,USP42 deubiquitinate TP53
- in pathway: Ub-specific processing proteases
USP10 specifically deubiquitinate p53 and not MDM2 (Yuan et al. 2010). USP24 and USP42 also can deubiquitinate p53, regulating the DNA damage response following UV-damage (Hock et al. 2011, Zhang et al. 2015).
Reaction - small molecule participants:
H2O [nucleoplasm]
Reactome.org reaction link: R-HSA-5689973
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Reaction input - small molecules:
water
Reaction output - small molecules:
Reactome.org link: R-HSA-5689973