Reaction: ATP13A1 transports Mn2+ from cytosol to ER lumen
- in pathway: Ion transport by P-type ATPases
Manganese-transporting ATPase 13A1 (ATP13A1) mediates the transport of manganese (Mn2+) into the endoplasmic reticulum. ATPase activity is required for cellular manganese homeostasis (Cohen et al. 2013).
Reaction - small molecule participants:
Pi [cytosol]
ADP [cytosol]
Mn2+ [endoplasmic reticulum lumen]
H2O [cytosol]
Mn2+ [cytosol]
ATP [cytosol]
Reactome.org reaction link: R-HSA-5692462
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Reaction input - small molecules:
water
manganese(2+)
ATP(4-)
Reaction output - small molecules:
hydrogenphosphate
ADP(3-)
manganese(2+)
Reactome.org link: R-HSA-5692462