Reaction: DLD dimer:2xFAD oxidises GCSH:DHLL to GCSH:lipoate
- in pathway: Glycine degradation
The last step in the glycine cleavage system is the reoxidation of the reduced lipoate (dihydrolipoyl group) attached to the H protein (GCSH:DHLL) catalysed by the L protein (mitochondrial dihydrolipoyl dehydrogenase, DLD) (Harris et al. 1997, Ciszak et al. 2006).
Reaction - small molecule participants:
H+ [mitochondrial matrix]
NADH [mitochondrial matrix]
NAD+ [mitochondrial matrix]
Reactome.org reaction link: R-HSA-5694018
======
Reaction input - small molecules:
NAD(1-)
Reaction output - small molecules:
hydron
NADH(2-)
Reactome.org link: R-HSA-5694018