Reaction: A4GNT transfers GlcNAc to core 2 mucins
- in pathway: O-linked glycosylation of mucins
Alpha-1,4-N-acetylglucosaminyltransferase (A4GNT) can catalyse the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched mucins, creating an alpha1,4-linkage with beta-Gal residues (arbitrarily named Core 2a mucins) (Nakayama et al. 1999, Zhang et al. 2001).
Reaction - small molecule participants:
UDP [Golgi lumen]
UDP-GlcNAc [Golgi lumen]
Reactome.org reaction link: R-HSA-5694487
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Reaction input - small molecules:
UDP-N-acetyl-alpha-D-glucosamine(2-)
Reaction output - small molecules:
UDP(3-)
Reactome.org link: R-HSA-5694487