Reaction: ACAD11 dehydrogenates BH-CoA
- in pathway: Mitochondrial Fatty Acid Beta-Oxidation
Acyl-CoA dehydrogenase family member 11 (ACAD11) is a mitochondrial membrane-bound enzyme that can catalyse the alpha, beta-dehydrogenation of acyl-CoA esters. ACAD11 shows highest expression in the brain and is shown to dehydrogenate the C22 acyl-CoA behenoyl-CoA (BH-CoA) to 2,3-dehydrobehenoyl-CoA (DBH-CoA) (He et al. 2011).
Reaction - small molecule participants:
DHB-CoA [mitochondrial matrix]
FADH2 [mitochondrial matrix]
FAD [mitochondrial matrix]
BH-CoA [mitochondrial matrix]
Reactome.org reaction link: R-HSA-5695989
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Reaction input - small molecules:
FAD(3-)
docosanoyl-CoA
Reaction output - small molecules:
2,3-dehydrobehenoyl-CoA
FADH2(2-)
Reactome.org link: R-HSA-5695989