Reaction: USP20, USP33 deubiquitinate ADRB2
- in pathway: Ub-specific processing proteases
USP20 and USP33 act as a regulators of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination of the beta-2 adrenergic receptor (ADRB2), prolonging agonist stimulation and inhibiting lysosomal trafficking (Berthouze et al. 2009).
Reaction - small molecule participants:
H2O [cytosol]
Reactome.org reaction link: R-HSA-5696968
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Reaction input - small molecules:
water
Reaction output - small molecules:
Reactome.org link: R-HSA-5696968