Reaction: USP10 deubiquitinates SNX3, CFTR
- in pathway: Ub-specific processing proteases
USP10 deubiquitinates and stabilizes endogenous SNX3 and consequently promotes cell surface expression of ENaC (Boulkroun et al. 2008). USP10 deubiquitinates CFTR in early endosomes thereby enhancing its endocytic recycling (Bomberger et al. 2009).
Reaction - small molecule participants:
H2O [cytosol]
Reactome.org reaction link: R-HSA-6782106
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Reaction input - small molecules:
water
Reaction output - small molecules:
Reactome.org link: R-HSA-6782106