Reaction: P6C transforms to 2AMAS
- in pathway: Lysine catabolism
The saccharopine pathway is the predominant lysine degradative pathway in extracerebral tissues, whereas the pipecolate pathway predominates in adult brain. (S)-1-piperideine-6-carboxylate (P6C), an intermediate of the pipecolate pathway, is in equilibrium with alpha-aminoadipate delta-semialdehyde (2AMAS), which connects the two degradative pathways. How peroxisomal P6C transports to mitochondrial 2AMAS is unknown (Hallen et al. 2013).
Reaction - small molecule participants:
2AMAS [mitochondrial matrix]
P6C [peroxisomal matrix]
Reactome.org reaction link: R-HSA-6783883
======
Reaction input - small molecules:
(S)-1-piperideine-6-carboxylate
Reaction output - small molecules:
L-allysine zwitterion
Reactome.org link: R-HSA-6783883