Reaction: Spontaneous hydrolysis of 1-pyrroline-3-hydroxy-5-carboxylate to 4-OH-L-glutamate semialdehyde
- in pathway: Glyoxylate metabolism and glycine degradation
The spontaneous hydrolysis of 1-pyrroline-3-hydroxy-5-carboxylate to form 4-OH-L-glutamate semialdehyde is inferred from the behavior of the analogous intermediate of proline catabolism (Moxley et al. 2011).
Reaction - small molecule participants:
4-OH-L-Glu semialdehyde [mitochondrial matrix]
1-pyrroline-3-hydroxy-5-carboxylate [mitochondrial matrix]
H2O [mitochondrial matrix]
Reactome.org reaction link: R-HSA-6784402
======
Reaction input - small molecules:
1-pyrroline-3-hydroxy-5-carboxylate
water
Reaction output - small molecules:
L-4-hydroxyglutamate semialdehyde zwitterion
Reactome.org link: R-HSA-6784402