Reaction: EKC complex threonylcarbamoylates A37 of tRNAs
- in pathway: tRNA modification in the nucleus and cytosol
As inferred from the yeast homologs (EKC complex, KEOPS complex, BUD32:CGI121:KAE1:PCC1), the EKC complex (LAGE3:OSGEP:TP53RK:TPRKB) transfers a threonylcarbamoyl group from L-threonylcarbamoyladenylate to adenosine-37 of tRNAs, yielding threonylcarbamoyladenosine-37.
Reaction - small molecule participants:
AMP [nucleoplasm]
L-threonylcarbamoyladenylate [nucleoplasm]
Reactome.org reaction link: R-HSA-6784494
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Reaction input - small molecules:
L-threonylcarbamoyladenylate
Reaction output - small molecules:
adenosine 5'-monophosphate(2-)
Reactome.org link: R-HSA-6784494