Reaction: FUK phosphorylates beta-Fuc to Fuc1P
- in pathway: GDP-fucose biosynthesis
In the GDP-fucose salvage pathway, beta-L-fucose (beta-Fuc) arising from the turnover of glycoproteins and glycolipids in the liver and other tissues is reutilised via a two-step pathway. The first step is the phosphorylation of L-fucose (L-Fuc) to fucose-1-phosphate (Fuc1P) by L-fucose kinase (FUK) (Hinderlich et al. 2002).
Reaction - small molecule participants:
ADP [cytosol]
Fuc1P [cytosol]
ATP [cytosol]
beta-Fuc [cytosol]
Reactome.org reaction link: R-HSA-6787540
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Reaction input - small molecules:
ATP(4-)
beta-L-fucose
Reaction output - small molecules:
ADP(3-)
beta-L-fucose 1-phosphate
Reactome.org link: R-HSA-6787540