Reaction: NUBPL transfers 4Fe-4S to NDUFV1, V2
- in pathway: Complex I biogenesis
In total, eight iron-sulfur (4Fe-4S) clusters are incorporated into six subunits (mitochondrial matrix-located NDUFS1, S2, S7, S8 and mitochondrial membrane-located V1 and V2) (Andrews et al. 2013). Incorporation into NDUFS1, S2, S7 and S8 is shown in a separate reaction. The mechanism of transfer is unknown. NDUFV1 also binds FMN (Schuelke et al. 1998).
Reaction - small molecule participants:
FMN [mitochondrial inner membrane]
Reactome.org reaction link: R-HSA-6788556
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Reaction input - small molecules:
FMN(3-)
Reaction output - small molecules:
Reactome.org link: R-HSA-6788556