Reaction: CK2:FACT phosphorylates TP53
- in pathway: Regulation of TP53 Activity through Phosphorylation
Casein kinase II (CK2), associated with the FACT2 complex, phosphorylates TP53 (p53) at serine residue S392, enhancing transcriptional activity of TP53 in response to UV irradiation (Keller et al. 2001, Keller and Lu 2002).
Reaction - small molecule participants:
ADP [nucleoplasm]
ATP [nucleoplasm]
Reactome.org reaction link: R-HSA-6805059
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Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-6805059