Reaction: AKT phosphorylates KAT6A
- in pathway: Regulation of TP53 Activity through Acetylation
Activated AKT phosphorylates the histone acetyltransferase KAT6A on threonine residue T369, preventing association of PML with the KAT6A complex and repressing KAT6A-mediated acetylation of TP53 (p53) (Rokudai et al. 2013).
Reaction - small molecule participants:
ADP [nucleoplasm]
ATP [nucleoplasm]
Reactome.org reaction link: R-HSA-6805640
======
Reaction input - small molecules:
ATP(4-)
Reaction output - small molecules:
ADP(3-)
Reactome.org link: R-HSA-6805640