Reaction: VKORC1L1 reduces vitamin K epoxide to MK4 (vitamin K hydroquinone)
- in pathway: Metabolism of vitamin K
VKORC1L1 (Vitamin K epoxide reductase complex subunit 1-like protein 1) in the endoplasmic reticulum catalyzes the reduction of MK4 epoxide to MK4, the active form of vitamin K. A physiological role for this reaction has not been established (Hammed et al. 2013; Tie et al. 2014; Westhofen et al. 2011).
Reaction - small molecule participants:
MK4 [endoplasmic reticulum lumen]
H+ [endoplasmic reticulum lumen]
MK4 epoxide [endoplasmic reticulum lumen]
Reactome.org reaction link: R-HSA-6806647
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Reaction input - small molecules:
hydron
2,3-epoxymenatetrenone
Reaction output - small molecules:
menaquinone-4
Reactome.org link: R-HSA-6806647