Reaction: ALDH3B2 oxidises HXAL to PALM
- in pathway: Sphingolipid metabolism
ALDH3B2 (aldehyde dehydrogenase family 3 member B2), associated with cytosolic lipid droplets, catalyzes the NAD-dependent oxdidation of HXAL (hexadecanal) to PALM (palmitate). A geranylgeranylated cysteine residue mediates the enzyme's association with the lipid droplet (Kitamura et al. 2013, 2015).
Reaction - small molecule participants:
PALM [lipid droplet]
H+ [cytosol]
NADH [cytosol]
H2O [cytosol]
HXAL [lipid droplet]
NAD+ [cytosol]
Reactome.org reaction link: R-HSA-6808464
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Reaction input - small molecules:
water
hexadecanal
NAD(1-)
Reaction output - small molecules:
hexadecanoic acid
hydron
NADH(2-)
Reactome.org link: R-HSA-6808464