Reaction: GDPD5 hydrolyzes GPCho
- in pathway: Glycerophospholipid catabolism
GDPD5 (Glycerophosphodiester phosphodiesterase domain-containing protein 5; GDE2) catalyzes the hydrolysis of GPCho (glycero-3-phosphocholine) to G3P (glycerol-3-phosphate) and Cho (choline). The localization and activity of human GDPD5 are inferred from those of its better-characterized mouse homolog (Gallazzini et al. 2008).
Reaction - small molecule participants:
Cho [cytosol]
G3P [cytosol]
H2O [cytosol]
GPCho [cytosol]
Reactome.org reaction link: R-HSA-6814132
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Reaction input - small molecules:
water
choline alfoscerate
Reaction output - small molecules:
choline
sn-glycerol 3-phosphate(2-)
Reactome.org link: R-HSA-6814132