Reaction: PXLP-K333-GADL1 decarboxylates CSA to HTAU
- in pathway: Degradation of cysteine and homocysteine
Acidic amino acid decarboxylase GADL1 (GADL1) can decarboxylate acidic amino acids such as cysteine sulfinic acid (CSA) to form hypotaurine (HTAU) (Liu et al. 2012, 2013). The dimeric structure of the enzyme is inferred from studies of its mouse homolog (Raasakka et al. 2018).
Reaction - small molecule participants:
HTAU [cytosol]
CO2 [cytosol]
CSA [cytosol]
Reactome.org reaction link: R-HSA-6814165
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Reaction input - small molecules:
3-sulfino-L-alanine(1-)
Reaction output - small molecules:
hypotaurine zwitterion
carbon dioxide
Reactome.org link: R-HSA-6814165