Reaction: UTP + D-glucose 1-phosphate <=> pyrophosphate + UDP-glucose
- in pathway: Glycogen synthesis
Cytosolic UDP-glucose pyrophosphorylase 2 (UGP2) catalyzes the reaction of UTP and glucose 1-phosphate to form UDP glucose and pyrophosphate (Knop and Hansen 1970; Duggleby et al. 1996). UGP2 is inferred to occur in the cell as a homooctamer from studies of its bovine homologue (Levine et al. 1969).
Reaction - small molecule participants:
PPi [cytosol]
UDP-D-glucose(2-) [cytosol]
G1P [cytosol]
UTP [cytosol]
PPi [cytosol]
UDP-D-glucose(2-) [cytosol]
G1P [cytosol]
UTP [cytosol]
Reactome.org reaction link: R-HSA-70286
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Reaction input - small molecules:
D-glucopyranose 1-phosphate(2-)
UTP(4-)
D-glucopyranose 1-phosphate(2-)
UTP(4-)
Reaction output - small molecules:
diphosphate(3-)
UDP-D-glucose(2-)
diphosphate(3-)
UDP-D-glucose(2-)
Reactome.org link: R-HSA-70286