Reaction: GPI dimer isomerizes Fru(6)P to G6P
- in pathway: TP53 Regulates Metabolic Genes
The reversible isomerization of Fru(6)P (fructose-6-phosphate) to form G6P (glucose-6-phosphate) is catalyzed by cytosolic GPI (phosphoglucose isomerase) dimer (Noltman 1972; Tsuboi et al. 1958; Xu and Beutler 1994).
Reaction - small molecule participants:
G6P [cytosol]
Fru(6)P [cytosol]
G6P [cytosol]
Fru(6)P [cytosol]
Reactome.org reaction link: R-HSA-70475
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Reaction input - small molecules:
beta-D-fructofuranose 6-phosphate(2-)
beta-D-fructofuranose 6-phosphate(2-)
Reaction output - small molecules:
alpha-D-glucose 6-phosphate(2-)
alpha-D-glucose 6-phosphate(2-)
Reactome.org link: R-HSA-70475