Reaction: 2 ATP + NH4+ + HCO3- => 2 ADP + orthophosphate + carbamoyl phosphate [mitochondrial]
- in pathway: Urea cycle
At the beginning of this reaction, 1 molecule of 'NH4+', 1 molecule of 'HCO3-', and 1 molecule of 'ATP' are present. At the end of this reaction, 1 molecule of 'Carbamoyl phosphate', 1 molecule of 'ADP', and 1 molecule of 'Orthophosphate' are present.
This reaction takes place in the 'mitochondrial matrix' and is mediated by the 'carbamoyl-phosphate synthase (ammonia) activity' of 'carbamoyl-phosphate synthetase I dimer'.
This reaction takes place in the 'mitochondrial matrix' and is mediated by the 'carbamoyl-phosphate synthase (ammonia) activity' of 'carbamoyl-phosphate synthetase I dimer'.
Reaction - small molecule participants:
Pi [mitochondrial matrix]
ADP [mitochondrial matrix]
CAP [mitochondrial matrix]
ATP [mitochondrial matrix]
NH4+ [mitochondrial matrix]
HCO3- [mitochondrial matrix]
Reactome.org reaction link: R-HSA-70555
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Reaction input - small molecules:
ATP(4-)
ammonium
hydrogencarbonate
Reaction output - small molecules:
hydrogenphosphate
ADP(3-)
carbamoyl phosphate(2-)
Reactome.org link: R-HSA-70555