Reaction: fumarylacetoacetate => fumarate + acetoacetate
- in pathway: Tyrosine catabolism
This is the final step of tyrosine degradation. Fumarylacetoacetase catalyzes the hydrolysis of 4-fumarylacetoacetate to form fumarate and acetoacetate (Labelle et al. 1993).
Reaction - small molecule participants:
ACA [cytosol]
FUMA [cytosol]
H2O [cytosol]
4FAA [cytosol]
Reactome.org reaction link: R-HSA-71181
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Reaction input - small molecules:
water
4-fumarylacetoacetate(2-)
Reaction output - small molecules:
acetoacetate
fumarate(2-)
Reactome.org link: R-HSA-71181