Reaction: AFMID hydrolyses NFK to L-KYN
- in pathway: Tryptophan catabolism
Cytosolic arylformamidase (AFMID) catalyzes the hydrolysis of formylkynurenine to yield formate and L-kynurenine. Human AFMID has been identified only as an open reading frame; its activity is inferred from that of its well-characterized mouse homologue (Pabarcus and Casida 2002).
Reaction - small molecule participants:
HCOOH [cytosol]
L-KYN [cytosol]
H2O [cytosol]
NFK [cytosol]
Reactome.org reaction link: R-HSA-71189
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Reaction input - small molecules:
water
N-formylkynurenine
Reaction output - small molecules:
formate
L-kynurenine
Reactome.org link: R-HSA-71189