Reaction: 3-hydroxykynurenine + H2O => 3-hydroxyanthranilate + alanine
- in pathway: Tryptophan catabolism
Cytosolic kynureninase catalyzes the hydrolysis of 3-hydroxy-L-kynurenine to form L-alanine and 3-hydroxyanthranilate.
Reaction - small molecule participants:
L-Ala [cytosol]
3HAA [cytosol]
3HKYN [cytosol]
H2O [cytosol]
Reactome.org reaction link: R-HSA-71217
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Reaction input - small molecules:
3-hydroxy-L-kynurenine
water
Reaction output - small molecules:
L-alanine zwitterion
3-hydroxyanthranilic acid
Reactome.org link: R-HSA-71217