Reaction: ALDH9A1 tetramer dehydrogenates TEABL to form TEABT
- in pathway: Carnitine synthesis
Cytosolic 4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) tetramer catalyzes the reaction of NAD+ and 4-trimethylammoniobutanal (TEABL) to form 4-trimethylammoniobutanoate (TEABT) and NADH + H+ (Koncitkova et al. 2019; Kurys et al. 1989; Vaz et al. 2000).
Reaction - small molecule participants:
H+ [cytosol]
TEABT [cytosol]
NADH [cytosol]
TEABL [cytosol]
H2O [cytosol]
NAD+ [cytosol]
Reactome.org reaction link: R-HSA-71260
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Reaction input - small molecules:
4-trimethylammoniobutanal
water
NAD(1-)
Reaction output - small molecules:
hydron
4-(trimethylammonio)butanoate
NADH(2-)
Reactome.org link: R-HSA-71260