Reaction: 3-Phospho-D-glycerate <=> 2-Phospho-D-glycerate
- in pathway: Glycolysis
Cytosolic phosphoglycerate mutase catalyzes the reversible isomerisation of 3- and 2-phosphoglycerate. The active form of the enzyme is a dimer. There are two isoforms of this enzyme, PGAM1 (isoform B, widely expressed in non-muscle tissue) and PGAM2 (isoform M, expressed in muscle) (Blouquit et al. 1988; Omenn and Cheung 1974; Repiso et al. 2005; Tsujino et al. 1993).
Reaction - small molecule participants:
2PG [cytosol]
3PG [cytosol]
Reactome.org reaction link: R-HSA-71654
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Reaction input - small molecules:
3-phosphonato-D-glycerate(3-)
Reaction output - small molecules:
2-phosphonato-D-glycerate(3-)
Reactome.org link: R-HSA-71654