Reaction: eIF5B:GTP is hydrolyzed and released
- in pathway: GTP hydrolysis and joining of the 60S ribosomal subunit
Once the 60S subunit joins the translation initiation complex, eIF5B hydrolyzes its GTP and is released from the now 80S monosome. The fully assembled 80s ribosome is now ready to start elongation of the polypeptide chain.
Reaction - small molecule participants:
Pi [cytosol]
Reactome.org reaction link: R-HSA-72671
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Reaction input - small molecules:
Reaction output - small molecules:
hydrogenphosphate
Reactome.org link: R-HSA-72671