Reaction: SLC35A2 exchanges UDP-Gal, UDP-GalNAc for UMP
- in pathway: Transport of nucleotide sugars
The human gene SLC35A2 encodes the UDP-galactose transporter (Miura et al. 1996). It is located on the Golgi membrane and mediates the antiport of UDP-Gal into the Golgi lumen in exchange for UMP. This transporter is also known to transport UDP-N-acetylgalactosamine (UDP-GalNAc) by the same antiport mechanism (Segawa et al. 2002).
Reaction - small molecule participants:
UMP [cytosol]
UMP [Golgi lumen]
Reactome.org reaction link: R-HSA-735702
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Reaction input - small molecules:
uridine 5'-monophosphate(2-)
Reaction output - small molecules:
uridine 5'-monophosphate(2-)
Reactome.org link: R-HSA-735702